ClotCare: Blood Clots, Stroke, Heart Attack
Wednesday, October 18, 2017
Home   |   DVT/PE   |   Blood Clots   |   Coumadin/Warfarin   |   New Patients   |   Self Testing   |   Email List   |   Donate

Pick a Topic:

Find info on a:

We subscribe to the HONcode principles of the HON Foundation. Click to verify.
ClotCare complies with the HONcode standard for trustworthy health
information:
verify here.

ClotCare is a member of the Coalition to Prevent Deep Vein Thrombosis (DVT Coalition)  ClotCare is a member organization of the Coalition to Prevent Deep Vein Thrombosis. Click here to learn more about the Coalition to Prevent Deep Vein Thrombosis and DVT Awareness Month, which is held each March.

Poor Early Anticoagulation Control Associated with Near 3-fold Increase in DVT Recurrence and Post-thrombotic Syndrome

Alex C. Spyropoulos, MD, FACP, FCCP
January, 2006

Review: van Dongen CJ, Prandoni P, Frulla M, Marchiori A, Prins MH, Hutten BA. Relation between quality of anticoagulant treatment and the development of the postthrombotic syndrome. J Thromb Haemost. 2005 May;3(5):939-42.

Van Dungen and colleagues evaluated 244 DVT patients on oral anticoagulation therapy (OAT). During a median follow-up of 4.9 years, and using a validated post-thrombotic syndrome (PTS) scoring system, they found that patients whose INRs were less than 2 more than 50% of the time were 2.7 times as likely to develop PTS (odds ratio 2.71, 95% confidence interval 1.44 - 5.10). Specifically, 81 patients (33%) developed PTS when INR < 2.0 more than 50% of the time.

Review: Palareti G, Legnani C, Cosmi B, Guazzaloca G, Cini M, Mattarozzi S. Poor anticoagulation quality in the first 3 months after unprovoked venous thromboembolism is a risk factor for long-term recurrence. J Thromb Haemost. 2005 May;3(5):955-61.

Palareti and colleagues reported on 297 patients with idiopathic venous thrombosis followed for 21 months after oral anticoagulation therapy (OAT) was stopped. Patients whose INRs were less than 1.5 the most often during the first 90 days of warfarin therapy were about 2.8 times as likely to have a recurrent venous thrombosis after OAT was stopped (relative risk 2.77, 95% confidence interval 1.49 - 5.18).

Ask a question about blood clots or anticoagulant medications Have questions? Ask ClotCare. Send questions by email to webmaster@clotcare.org.

ClotCare is a 501(c)(3) non-profit organization generously supported by your tax-deductible donations and grants from our industry supporters.

Blood Clot Activities Calendar

New Postings:

World Thrombosis Day - Oct. 13, 2017

Rivaroxaban or Warfarin in Stable Coronary Artery Disease – Should the COMPASS Study Lead Us Back to the Future?

Click here to view full list of new postings
ClotCare Home | New Postings | Patient Postings | Clinician Postings | Join Our Email List | Useful Web Links
CE Opportunities | Training Programs | DVT & PE Stories | Editorial Board | Financial Support
About ClotCare | DVT Coalition | Donate to ClotCare | Contact Us
Key topics discussed on ClotCare include: Blood Clots | Deep Vein Thrombosis (DVT) | Pulmonary Embolism (PE) | Atrial Fibrillation (A. Fib or AF) | Heart Attack | Stroke | Transient Ischemic Attack (TIA) | Mini Stroke | Bleeding Complications | Vascular Surgery | Surgical Blood Clot Removal | Warfarin | Coumadin | Lovenox | Low Molecular Weight Heparin (LMWH) | Heparin | Anticoagulants | Plavix | Aspirin | Antiplatelets | Blood Thinners
Copyright 2000-2014 by ClotCare. All rights reserved.
Terms, Conditions, & Privacy | Image Copyright Information
19260 Stone Oak Parkway, Suite 101 | San Antonio, TX 78258 | 210-495-4335
Send comments to webmaster@clotcare.org.
Wednesday, October 18, 2017